欢迎访问《茶叶科学》,今天是

茶叶科学 ›› 2011, Vol. 31 ›› Issue (3): 247-254.doi: 10.13305/j.cnki.jts.2011.03.011

• • 上一篇    下一篇

茯砖茶及其配方对脂肪变性L-02肝细胞中TG含量的影响

徐小江1,2, 黄建安1,2, 肖力争1, 袁勇1,2, 肖文军1,2*   

  1. 1. 湖南农业大学园艺园林学院,湖南 长沙 410128;
    2. 湖南农业大学茶学教育部重点实验室,湖南 长沙 410128
  • 收稿日期:2010-10-25 修回日期:2010-12-31 出版日期:2011-06-15 发布日期:2019-09-06
  • 通讯作者: xiaowenjun88@sina.com
  • 作者简介:徐小江(1986— ),男,湖南邵阳人,硕士研究生,主要从事茶及植物功能作用研究。
  • 基金资助:
    湖南省重大科技专项“茯茶产业化关键技术研究与示范”(2008FJ1005)、国家“十二五”支撑计划资助项目(2011BAD10B00)、国家APEC基金资助项目(200847)、中国博士后基金资助项目(20070410985)

Effects of Fu Brick Tea and Its Formula on the Content of TG in L-02 Steatotic Hepatocytes

XU Xiao-jiang1,2, HUANG Jian-an1,2, XIAO Li-zheng1, YUAN Yong1,2, XIAO Wen-jun1,2*   

  1. 1. College of Horticultural and Landscape, Hunan Agricultural university, Changsha 410128, China;
    2. Key Lab of Tea Science of Ministry of Education, Hunan Agricultural University, Changsha 410128, China
  • Received:2010-10-25 Revised:2010-12-31 Online:2011-06-15 Published:2019-09-06

摘要: 利用1mL/L的20%医用脂肪乳剂处理L-02肝细胞48h复制非酒精性脂肪变性肝细胞,然后加入不同浓度的提取物及配方分别处理24h和48h,全自动生化分析仪检测肝细胞内的甘油三酯(TG)水平,探讨茯砖茶提取物和两个配方对脂肪变性L-02肝细胞内TG的影响。结果显示,茯砖茶提取物和配方1与自然恢复组比较均可显著降低脂肪变性肝细胞内TG的水平(P<0.05),而与血脂康组比较无显著差异(P>0.05),显示出茯砖茶和配方1具有广阔的开发应用前景。

关键词: 茯砖茶, 脂肪变性, L-02肝细胞, 配方, 甘油三酯

Abstract: Using 1mL/L of 20% medical fat emulsion to process L-02 liver cells for 48h in order to replicate non-alcoholic fatty degeneration of liver cells, and then adding different concentrations of extracts and its formulas to process separately for 24h and 48h, automatic biochemical analyzer detects the level of triglycerides (TG) in liver cells, investigate the effects of Fu Brick Tea extraction and the two formulas on the content of TG in L-02 Steatotic Hepatocytes. Results showed that Fu brick tea extraction and formula 1 can significantly lower TG levels in fatty liver cells(P<0.05), while comparing with the Xue Zhi Kang group, those two groups presented no significant difference (P>0.05). Accordingly, Fu brick tea and formula 1 reflect a wide prospect of development and application.

Key words: Fu brick tea, hepatocytes steatosis, L-02 hepatocyte, formula, triglyceride

中图分类号: