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茶叶科学 ›› 2019, Vol. 39 ›› Issue (3): 231-246.doi: 10.13305/j.cnki.jts.2019.03.001

• •    下一篇

茶多酚对动脉粥样硬化的预防作用与机理研究进展

张姝萍,王岳飞,徐平   

  1. 浙江大学茶学系,浙江 杭州 310058
  • 收稿日期:2018-07-04 修回日期:2018-09-07 出版日期:2019-06-15 发布日期:2019-06-15
  • 通讯作者: 张姝萍, E-mail:996829620@qq.com
  • 作者简介:张姝萍,女,硕士研究生,主要从事天然产物与人体健康及其机理研究。*通信作者:zdxp@zju.edu.cn
  • 基金资助:
    国家广东省产学研合作项目(2016B090918118)

Prevention of Tea Polyphenols on Atherosclerosis and Relative Mechanisms

ZHANG Shuping, WANG Yuefei, XU Ping   

  1. Department of Tea Science, Zhejiang University, Hangzhou 310058, China
  • Received:2018-07-04 Revised:2018-09-07 Online:2019-06-15 Published:2019-06-15
  • Contact: ZHANG Shuping, E-mail:996829620@qq.com

摘要: 动脉粥样硬化是多种心血管疾病的重要病理基础,对心脑血管的损害可累及全身各个器官。茶多酚能 够通过抗炎、调节血脂水平、抑制LDL 氧化修饰、改善内皮功能、保持斑块稳定性等不同途径有效预防动脉 粥样硬化。本文就近年来茶多酚对动脉粥样硬化的预防功能与机理方面的研究进行综述。

关键词: 动脉粥样硬化, 茶多酚, 心血管, 抗炎, 平滑肌细胞增殖

Abstract: Atherosclerosis is the pathological basis of many cardiovascular diseases. Its injury to the cardiovascular could cause damage to other organs. Numerous data had indicated that tea polyphenols have a good preventive effect on atherosclerosis, such as anti-inflammatory, regulating blood lipid levels, inhibiting LDL oxidation, improving endothelial function and maintaining the stability of atherosclerotic plaque. The aim of this article is to review the health benefits of tea polyphenols against atherosclerosis and to outline the molecular mechanisms of tea polyphenols in atherosclerosis prevention.

Key words: atherosclerosis, tea polyphenols, cardiovascular, anti-inflammatory, vascular smooth muscle cell proliferation

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