基于CiteSpace的茶黄素研究现状可视化分析

茶叶科学 ›› 2022, Vol. 42 ›› Issue (1): 131-139.

基于CiteSpace的茶黄素研究现状可视化分析

周宇飞¹, 周琳^2,*, 禹利君^1,3,*, 徐帅¹, 杨益欢¹

1.湖南农业大学茶学教育部重点实验室/国家植物功能成分利用工程技术研究中心,湖南长沙 410128;
2.湖南省农业科学院茶叶研究所,湖南长沙 410145;
3.植物功能成分利用省部共建协同创新中心,湖南长沙 410128

收稿日期:2021-06-18 修回日期:2021-11-03 出版日期:2022-02-15 发布日期:2022-02-18
通讯作者: *36078882@qq.com;yulijun_tea@qq.com
作者简介:周宇飞,男,硕士研究生,主要从事茶叶功能成分及药理研究。
基金资助:
国家重点研发计划（2018YFC1604403）、湖南省科技厅黑茶重点研发项目（2017NK2180）、湖南省大学生创新创业训练计划（201910537089）、财政部和农业农村部：国家现代农业产业技术体系（CARS-19）

Visualization Analysis in Research Status of Theaflavins Based on CiteSpace

ZHOU Yufei¹, ZHOU Lin^2,*, YU Lijun^1,3,*, XU Shuai¹, YANG Yihuan¹

1. Key Laboratory of Tea Science of Ministry of Education/National Research Center of Engineering and Technology for Utilization of Functional Ingredients for Botanical, Hunan Agricultural University, Changsha 410128, China;
2. Tea Research Institute of Hunan Academy of Agricultural Sciences, Changsha 410145, China;
3. Co-Innovation Center of Education Ministry for Utilization of Botanical Functional Ingredients, Changsha 410128, China

Received:2021-06-18 Revised:2021-11-03 Online:2022-02-15 Published:2022-02-18

摘要/Abstract

摘要： 为把握茶黄素研究的进展和热点,客观反映不同国家、作者、研究机构以及期刊在该领域的影响力,本研究运用文献计量学和CiteSpace可视化分析软件,对1964—2021年被WOS（Web of Science）数据库收录的725篇和被CNKI（China National Knowledge Infrastructure,中国知网）数据库收录的391篇茶黄素（Theaflavin/Theaflavins,TF/TFs）文献进行分析。结果表明,研究报道茶黄素最多的国家依次为中国、印度、美国和日本;日本长崎大学的Tanaka研究最为深入;与茶黄素类相关的儿茶素氧化产物研究报道最多;刘仲华、江和源、屠幼英是国内茶黄素研究的引领者;《茶叶科学》和《Food Science Technology》是茶黄素发文量最高的期刊;关键词分析显示中文文献研究侧重于茶黄素的制备分离和其对红茶品质的影响,英文文献侧重于茶黄素的药理研究,且茶黄素的制备分离及其药理功效仍为未来研究的热点。

关键词: 茶黄素, CiteSpace, 研究热点, WOS, 中国知网, 可视化

Abstract: Aiming to grasp the progress and hotspots of theaflavin research and objectively reflect the influence of different countries, authors, research institutions and journals in this field, bibliometrics and CiteSpace.5.7.R5W visualization analysis software were used in this study to analyze 725 and 391 Theaflavin/Theaflavins (TF/TFs) literatures collected by Web of Science (WOS) and China National Knowledge Infrastructure (CNKI) from 1964 to 2021. It was found that China, India, the United States and Japan were the countries with the most research on theaflavin. Tanaka of Nagasaki University in Japan had the most researches. The catechin oxidation products related to theaflavins had been reported the most. Liu Zhonghua, Jiang Heyuan and Tu Youying were the leaders of theaflavins research in China. Food Science Technology and Journal of Tea Science were the English and Chinese journals with the highest publication volume of theaflavin. Keyword analysis showed that Chinese literature mainly focused on the preparation and separation of theaflavins and their effects on the quality of black tea. English literature focused on the pharmacological research of theaflavins, and the preparation and pharmacological effects of theaflavins were still the research hotspots in the future.

Key words: theaflavins, CiteSpace, research hotspot, Web of Science, CNKI, visualization

中图分类号:

S571.1

周宇飞, 周琳, 禹利君, 徐帅, 杨益欢. 基于CiteSpace的茶黄素研究现状可视化分析[J]. 茶叶科学, 2022, 42(1): 131-139.

ZHOU Yufei, ZHOU Lin, YU Lijun, XU Shuai, YANG Yihuan. Visualization Analysis in Research Status of Theaflavins Based on CiteSpace[J]. Journal of Tea Science, 2022, 42(1): 131-139.

参考文献

[1] Tanaka T, Matsuo Y.Production mechanisms of black tea polyphenols[J]. Chemical & Pharmaceutical Bulletin, 2020, 68(12): 1131-1142.
[2] Zhu K, Ouyang J, Huang J A, et al.Research progress of black tea thearubigins: a review[J]. Critical Reviews in Food Science and Nutrition, 2021, 61(9): 1556-1566.
[3] 郑艳超, 於天, 郑志刚, 等. 茶黄素生物活性与开发应用的研究进展[J]. 中草药, 2020, 51(23): 6095-6101.
Zheng Y C, Yu T, Zheng Z G, et al.Research progress on biological activity and application development of theaflavins[J]. Chinese Traditional and Herbal Drugs, 2020, 51(23): 6095-6101.
[4] Gothandam K, Ganesan V S, Ayyasamy T, et al.Antioxidant potential of theaflavin ameliorates the activities of key enzymes of glucose metabolism in high fat diet and streptozotocin - induced diabetic rats[J]. Redox Rep, 2019, 24(1): 41-50.
[5] 周盈, 黄倩, 张甜, 等. TFDG对IL-1β体外诱导大鼠软骨细胞炎性损伤的保护作用研究[J]. 茶叶科学, 2017, 37(3): 290-298.
Zhou Y, Huang Q, Zhang T, et al.Research on the protective effects of TFDG on IL-1β-induced inflammatory injury in rat chondrocytes in vitro[J]. Journal of Tea Science, 2017, 37(3): 290-298.
[6] Jang M S, Park Y I, Cha Y E, et al.Tea polyphenols EGCG and theaflavin inhibit the activity of SARS-CoV-2 3CL-Protease in vitro[J]. Evidence-Based Complementary and Alternative Medicine, 2020, 2020: 5630838. doi: 10.1155/2020/5630838.
[7] Takemoto M, Takemoto H.Synthesis of theaflavins and their functions[J]. Molecules, 2018, 23(4): 918. doi: 10.3390/molecules23040918.
[8] O'Neill E J, Termini D, Albano A, et al. Anti-Cancer properties of theaflavins[J]. Molecules, 2021, 26(4): 987. doi: 10.3390/molecules26040987.
[9] 宫连瑾, 薄佳慧, 杜哲儒, 等. 提高中小叶种红茶茶黄素含量研究进展[J]. 茶叶通讯, 2020, 47(3): 375-381.
Gong L J, Bo J H, Du Z R, et al.Research progress in increasing the content of theaflavin in black tea of middle and small leaves[J]. Journal of Tea Communication, 2020, 47(3): 375-381.
[10] 雷时成, 孙大利, 王亚洁, 等. 茶黄素双没食子酸酯的生物活性及其作用机制[J]. 食品与机械, 2020, 36(2): 229-236.
Lei S C, Sun D L, Wang Y J, et al.Biological activities of theaflavin-3,3'-digallate and its mechanism of action[J]. Food & Machinery, 2020, 36(2): 229-236.
[11] 陈悦, 陈超美, 刘则渊, 等. CiteSpace知识图谱的方法论功能[J]. 科学学研究, 2015, 33(2): 242-253.
Chen Y, Chen C M, Liu Z Y, et al.The methodology function of CiteSpace mapping knowledge domains[J]. Studies in Science of Science, 2015, 33(2): 242-253.
[12] Chen C M.Science mapping: a systematic review of the literature[J]. Journal of Data and Information Science, 2017, 2(2): 1-40.
[13] 银霞, 黄建安, 黄静, 等. 基于CiteSpace可视化分析的茶叶香气研究进展[J]. 茶叶科学, 2020, 40(2): 143-156.
Ying X, Huang J A, Huang J, et al.Research progress of tea aroma based on CiteSpace visual analysis[J]. Journal of Tea Science, 2020, 40(2): 143-156.
[14] 尹美玲, 宋颜君, 许利嘉, 等. 基于文献计量学的绿茶研究热点分析[J]. 中国现代中药, 2021, 23(7): 1294-1298.
Yin M L, Song Y J, Xu L J, et al.Research progress of tea aroma based on CiteSpace visual analysis[J]. Modern Chinese Medicine, 2021, 23(7): 1294-1298.
[15] 丁阳平, 刘仲华, 黄建安, 等. 聚酰胺分离纯化茶黄素类物质研究[J]. 食品科学, 2007, 28(12): 55-57.
Ding Y P, Liu Z H, Huang J A, et al.Study on separation and purification of theaflavins by polyamide[J]. Food Science, 2007, 28(12): 55-57.
[16] 陈东生, 王坤波, 李勤, 等. 丰水梨多酚氧化酶基因的克隆与原核表达[J]. 茶叶科学, 2015, 35(1): 17-23.
Chen D S, Wang K B, Li Q, et al.The cloning and prokaryotic expression of polyphenol oxidase gene in pear (Pyrus Pyrifolia Nakai)[J]. Journal of Tea Science, 2015, 35(1): 17-23.
[17] 张静, 黄建安, 蔡淑娴, 等. 茶黄素与EGCG抑制体内外β-淀粉样蛋白1-42水平及其诱导的神经细胞氧化损伤[J]. 茶叶科学, 2016, 36(6): 655-662.
Zhang J, Huang J A, Cai S X, et al.Theaflavins and EGCG protect SH-SY5Y cells from oxidative damage induced by amyloid-β 1-42 and inhibit the level of Aβ₄₂ in vivo and in vitro[J]. Journal of Tea Science, 2016, 36(6): 655-662.
[18] Kusano R, Matsuo Y, Saito Y, et al.Oxidation mechanism of black tea pigment theaflavin by peroxidase[J]. Tetrahedron Lett, 2015, 56(36): 5099-5102.
[19] Miyata Y, Tamaru S, Tanaka T, et al.Theaflavins and theasinensin a derived from fermented tea have antihyperglycemic and hypotriacylglycerolemic effects in KK-A(y) mice and sprague-dawley rats[J]. J Agric Food Chem, 2013, 61(39): 9366-9372.
[20] Li B R, Fu L, Kojima R, et al.Theaflavins prevent the onset of diabetes through ameliorating glucose tolerance mediated by promoted incretin secretion in spontaneous diabetic Torii rats[J]. J Funct Food, 2021, 86: 8. doi: 10.1016/j.jff.2021.104702.
[21] Ma H, Hu Y Z, Zhang B W, et al.Tea polyphenol-gut microbiota interactions: hints on improving the metabolic syndrome in a multi-element and multi-target manner[J]. Food Sci Human Wellness, 2022, 11(1): 11-21.
[22] Kashif M, Imran A, Saeed F, et al.Catechins, theaflavins and ginger freeze-dried extract based functional drink significantly mitigate the hepatic, diabetic and lipid abnormalities in rat model[J]. Cell Mol Biol, 2021, 67(1): 132-141.
[23] Cai X Q, Liu Z H, Dong X, et al.Hypoglycemic and lipid lowering effects of theaflavins in high-fat diet-induced obese mice[J]. Food Funct, 2021, 12(20): 9922-9931.
[24] Sirotkin A V, Kolesarova A.The anti-obesity and health-promoting effects of tea and coffee[J]. Physiol Res, 2021, 70(2): 161-168.
[25] Zeng J, Deng Z H, Zou Y X, et al.Theaflavin alleviates oxidative injury and atherosclerosis progress via activating microRNA-24-mediated Nrf2/HO-1 signal[J]. Phytother Res, 2021, 35(6): 3418-3427.
[26] Takashima Y, Ishikawa K, Miyawaki R, et al.Modulatory effect of theaflavins on apical sodium-dependent bile acid transporter (ASBT) activity[J]. J Agric Food Chem, 2021, 69(33): 9585-9596.