表儿茶素的碳酰化改性及其紫外吸收和抗氧化活性

doi:10.13305/j.cnki.jts.2024.03.002

Abstract

Abstract: In order to enhance the UV absorption characteristic of epicatechin derivatives and improve their solubility in non-polar solvents such as oils and fats, 2,2'-di(p-hydroxybenzocarbonyl)-epicatechin was synthesized from epicatechin and p-hydroxybenzoic acid using methane sulfonic acid as solvent and catalyst. The target products were separated by column chromatography, and the purity was verified by high performance liquid chromatography (HPLC), and the structure of the target products were verified by UV-vis, FT-IR, ¹H NMR, ¹³C NMR, LC-MS spectroscopy. The UV absorption characteristic of 2,2'-di(p-hydroxybenzocarbonyl)-epicatechin and its ability to scavenge ABTS⁺·, DPPH· and O^2-· were evaluated. The results show that the synthesized 2,2'-di(p-hydroxybenzocarbonyl)-epicatechin had similar UV absorption and comparable molar absorptivity to OMC, the commonly used UV absorber, and is expected to be an excellent UV absorber in the UVB band. 2,2'-di(p-hydroxybenzocarbonyl)-epicatechin had good antioxidant activity in vitro, and its antioxidant capacity in vitro was higher than that of VC and slightly lower than that of epicatechin, which is expected to be used for cosmetic applications.

Key words: epicatechin, carbonylation, modification, UV absorption, cosmetic

CLC Number:

LEI Xiang, ZHANG Minfeng, LIN Hui, WANG Lili, ZHENG Deyong. Carbonylation Modification of Epicatechin and Its Activities of UV Absorption and Antioxidant[J]. Journal of Tea Science, 2024, 44(3): 493-500.

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Carbonylation Modification of Epicatechin and Its Activities of UV Absorption and Antioxidant

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